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2 ﹒ Itagaki F，Homma M，Yuzawa K，et al ﹒ Effect of lansoprazole and rabeprazole on tacrolimus phar macokinetics in healthy volunteers with CYP2C19mutations ﹒ J Phar m Phar macol，2004，56.4 ﹒ Hosohata K，Masuda S，Ogura Y，et al ﹒ Interaction bet ween tacrolimus and lansoprazole，but not rabeprazoleinliving‐donor liver transplant patients with defects of CYP2C19and CYP3A5.Drug Metab Phar macokinet，2008，23.