46﹒Efficacy Promoting Effect of Hyaluronan on Pilocarpine Nitrate Eye Drops

Hyaluronan（HA）is a natural occuring biopolymer belonging to a family of mucopolysac charide，widely exists in human and vertebrates ． Due to its high molecular weight and long lin ear molecular chain with thousands of anions。Hyaluronan solution is very viscous and lubri cious ． The unique physical properties and high biocompatibility with tissues of human。Make it suitable for various medical and pharmaceutical applications ． Hyaluronan was first used as a viscoelastic agent in ophthalmological surgery in 1970 ’ s。