[治疗]氟硝西泮，氟硝安定Flunitrazepam

目前尚无因应用本品致胎儿畸形的报道。孕妇口服本品1mg后12小时左右，脐血／母血中药物浓度比值在早孕期为0.5，晚孕期为0.22。羊水／母血中药物浓度比值范围为0.02～0.07 ［ 1 ］。氟硝西泮能入乳，口服单剂本品2mg后11小时、15小时、27小时和39小时，平均乳汁／母血中药物浓度比值分别为0 ﹒。Use of benzodiazepines during pregnancy，labour and lactation，with special reference to pharmacokinetic consideration .