27﹒Studies on the Mechanismand Pharmacodynamics of Hy aluronic Acid Used as Vehicle in Eye Drops

The aim of this article was to review the effect of hyaluronic acid used as vehicle for ocular drug delivery ． Two experiments were conducted to analyze the mechanism and the application of hyaluronic acid in eye drops ． The concentration of timolol maleate in aqueous homor after single instillation of the timolol maleate eye drops vehicled by hyaluronan was compared with.Membrane adhesion as well as drug interaction ． The eye drops vehi cled with hyaluronic acid have higher bioavailability，which will contribute to a broad prospect in application ．.