HLA-B27只提供强直性脊柱炎遗传风险的16%~50%,可能还存在其他因素如其他HLA基因。0101、HLA-DR4、MHC(HLA class)-Ⅱ、低分子蛋白酶体(low molecular weight proteasome,LMP)、抗原加工相关转运子(transporter associated with antigen processing。TAP)、主要组织相容性复合体Ⅰ类相关基因A(major histocompatibility complex class I chain-relate ......