LevofloxacinistheL‐isomeroftheracemateofloxacinwith tivityagainstgram‐negativeandgram‐positiveorganisms,whoseantimicrobialactivityisasmu astwotimescomparedwithofloxacin [ 1。2 ] . Itisreportedthatlevofloxacinhasg penetration [ 3 ] whentopicallyapplied,buth ......