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Drug-protein adducts：an industry perspective on minimizing the potential for drug bioactivation in drug discovery and development .Characterization of novel glutathione adducts of a non-nucleosidereverse transcriptase inhibitor，6-chloro-4-(cyclopropylethinyl)-4-trifluoromethyl-3, 4-dihydro-2（1H）-quinazolinone（DP-961），in rats .Beiley MJ, Dickinson RG . Limitations of hepatocytes and liver homogenates in modeling in vivo formation of acyl glucuronide-derived drug-protein adducts .