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Plasma lipoprotein-associated phospholipase A2 is inversely correlated with proprotein convert asesubtilisin-k type.To reduce low-density lipoprotein cholesterol in patients with heterozygous familial hypercholesterolaemia on stable statin dose with or without ezetimibe therapy ： a phase 2 randomised controlled trial .Marina Cuchel MD . Efficacy and safety of a microsomal triglyceride transfer protein inhibitor in patients with homozygous familial hypercholesterolaemia ： a single-arm ， open-label ， phase 3 study .